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Radiation Protection Dosimetry Advance Access published online on October 15, 2008
Radiation Protection Dosimetry, doi:10.1093/rpd/ncn267
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© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

EXPOSURE ASSESSMENT: IMPLICATIONS FOR EPIDEMIOLOGICAL STUDIES OF IONISING RADIATION

Colin R. Muirhead*

Health Protection Agency, Radiation Protection Division, Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 0RQ, UK

* Corresponding author: colin.muirhead{at}hpa.org.uk

Quantitative estimates of ionising radiation exposure are often available for use in epidemiological studies. However, depending on the context, the quality of the exposure estimates can vary. For example, the estimates may be specific to individuals in the study or generic values averaged over populations; unavailable for some of the potential study subjects or vary in their form between individuals; based on contemporary measurements or assessed retrospectively; based on measurements alone, on surrogate measures of exposure, or on an exposure assessment model; or, as is often the case, cover one source of radiation exposure rather than all of them. Various ways in which ionising radiation exposures have been assessed are illustrated through reference to some studies of childhood leukaemia, concerning environmental, medical, natural and parental occupational exposures. Based on this, implications for the interpretation of radiation epidemiological studies are discussed.


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