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Radiation Protection Dosimetry 62:77-79 (1995)
© 1995 Oxford University Press

The Role of Thymus in the Appearance of Immunologic Effects of Low Dose Irradiation

A.A. Yarilin, N.I. Sharova, O.I. Kuzmenok, N.I. Kotchergina, M.F. Nikonova, M.M. Litvina and N.P. Savina

Serum levels of thymic hormones decreased in persons exposed to low doses of ionising radiation after the Chernobyl accident. The probable causes of secretory deficiency of the thymus are increased production of autoantibodies reactive to thymic epithelial cells (hormone producers) and general hormonal imbalance. The main consequence of the decrease of thymic hormone level is hypofunction of T cells displaying a decreased proliferative response on stimulation by various factors.


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