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Radiation Protection Dosimetry Advance Access originally published online on December 21, 2006
Radiation Protection Dosimetry 2006 122(1-4):506-508; doi:10.1093/rpd/ncl392
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Calculated microdosimetric characteristics of 125I and 103Pd brachytherapy seeds at different depths in water

Cheng-Shie Wuu1,* and Jing Chen2

1 Department of Radiation Oncology, Columbia University, New York, NY 10032, USA
2 Radiation Protection Bureau, Health Canada, Ottawa K1A 1C1, Canada

* Corresponding author: csw6{at}columbia.edu


  Abstract

Both 125I and 103Pd sources have been widely used in the permanent prostate implant. An important consideration for the choice of brachytherapy sources is the relative biological effectiveness (RBE) for the source/seed used in the implantation. As RBE is closely related to the microdosimetric parameter, it is desirable to calculate the dose mean lineal energies for both 125I and 103Pd at various radial distances to the seed surface. Monte Carlo simulation was performed for photons emitted from 125I and 103Pd. Energy depositions from photons and all their secondary electrons were tracked. Dose distributions of lineal energy, d(y), were calculated for spheres of 1 µm in diameter and at various radial distances to the seed surface. From the dose distribution of lineal energy, the dose mean lineal energy, yD, was derived. The results showed that the radiation qualities are constant in the distance range from 0.5 to 5 cm. In this distance range, the quality factor, relative to gamma rays from 60Co, is 2.2 for 125I and 2.5 for 103Pd.


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