Skip Navigation

Radiation Protection Dosimetry 2005 114(1-3):424-431; doi:10.1093/rpd/nch552
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Ruschin, M.
Right arrow Articles by Andersson, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ruschin, M.
Right arrow Articles by Andersson, I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Using simple mathematical functions to simulate pathological structures—input for digital mammography clinical trial

M. Ruschin1,*, A. Tingberg1, M. Båth2, A. Grahn1, M. Håkansson2, B. Hemdal1 and I. Andersson3

1 Department of Medical Radiation Physics, Lund University, Malmö University Hospital, SE-205-02 Malmö, Sweden
2 Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, SE-41345 Göteborg, Sweden
3 Department of Diagnostic Radiology, Lund University, Malmö University Hospital, SE-205-02 Malmö, Sweden

* Corresponding author: mark.ruschin{at}rfa.mas.lu.se

In this study a set of structures has been simulated to represent a range of clinically relevant breast cancer mammographic lesions including solid tumours and microcalcifications. All structures have been created using simple random-based mathematical functions and have been inserted into a subset of digital mammography images at appropriate contrast levels into various regions of the breast, including dense fibroglandular and adipose tissue. These structures and their appearance in these clinical images were evaluated in terms of how realistic they looked. They will be used as the input to a large-scale clinical trial designed to examine the effect of significant dose reduction in digital mammography by comparing the detectability of such structures in images acquired at full and quarter automatic exposure control (AEC) dose level and in images with simulated noise levels in between.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.