Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (13)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Morlier, J.P.
Right arrow Articles by Masse, R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Morlier, J.P.
Right arrow Articles by Masse, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Radiation Protection Dosimetry 56:93-97 (1994)
© 1994 Oxford University Press

Lung Cancer Incidence After Exposure of Rats to Low Doses of Radon: Influence of Dose Rate

J.P. Morlier, M. Morin, G. Monchaux, P. Fritsch, J.F. Pineau, J. Chameaud, J. Lafuma and R. Masse

To study the effect on lung cancer incidence of a long exposure to low levels of radon, 500 male 3-month-old Sprague-Dawley rats, were exposed to a cumulative dose of 25 WLM of radon and its daughters, 6 hours a day, 5 days a week, during 18 months. Exposure conditions were controlled in order to maintain a defined PAEC: 42 x 10-6 J.m-3 (2 WL), in the range of domestic and environmental exposures. Animals were kept until they died or given euthanasia when moribund. Mean survival times were similar in both irradiated and control groups: 828 days (SD = 169) and 830 days (SD = 137), as well as lung cancer incidence, 0.60% at 25 WLM and 0.63% for controls. The incidence of lung lesions was compared statistically with controls and those previously obtained at cumulative exposures of 25 and 50 WLM delivered over a 4-6 month period, inducing a significant increase of lung cancer, 2.2% and 3.8% respectively. Such a comparison showed a decreased lung cancer incidence related to a decrease in the dose rate for low levels of radon exposure.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Radiat Prot DosimetryHome page
H. Fakir, W. Hofmann, and R. S. Caswell
Radon progeny microdosimetry in human and rat bronchial airways: the effect of crossfire from the alveolar region
Radiat Prot Dosimetry, June 1, 2008; 130(2): 149 - 161.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.