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Radiation Protection Dosimetry Advance Access originally published online on March 3, 2007
Radiation Protection Dosimetry 2007 125(1-4):500-505; doi:10.1093/rpd/ncm168
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© The Author 2007. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Biokinetic modelling of natural thorium in humans by ingestion

W. B. Li*, W. Wahl, U. Oeh, V. Höllriegl and P. Roth

GSF-National Research Center for Environment and Health, Institute of Radiation Protection, Ingolstädter Landstraße 1 D-85764 Neuherberg, Germany

*Corresponding author: wli{at}gsf.de

The retention of naturally occurring thorium (228Th, 230Th, 232Th) in model compartments and its daily urinary and faecal excretion after acute and chronic injections and ingestions were calculated for male and female subjects of six age groups based on the current age-dependent biokinetic model for thorium (Th) recommended by the International Commission on Radiological Protection (ICRP). The results are tabulated in a database. The calculated contents of 228,230,232Th in organs or tissues using their reference concentrations in foodstuffs for the European population are compared with autopsy data. The model prediction of 232Th in whole body for a 50-year-old unexposed person is 22 mBq, 86% of that in skeleton, 9.7% in other soft tissues, 3.4% in liver, 0.7% in kidneys and 0.01% in blood. The modelling predicts lower contents of the natural Th isotopes in whole body, especially in blood compared with measured data for the unexposed public. Modelled 232Th daily urinary excretions are 5 to 10 times less than bio-assay data from the authors' own laboratory.


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