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Radiation Protection Dosimetry Advance Access originally published online on October 21, 2005
Radiation Protection Dosimetry 2006 118(1):70-77; doi:10.1093/rpd/nci342
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

The European Radiobiology Archives (ERA)—content, structure and use illustrated by an example

G. B. Gerber1,*, R. R. Wick2, A. M. Kellerer3, J. W. Hopewell4, V. Di Majo5, N. Dudoignon6, W. Gössner7 and J. Stather8

1 B-2400 Mol, De Heylanden 7, (European Late Effects Project Group EULEP), Belgium
2 GSF-Forschungszentrum für Umwelt und Gesundheit, Institut für Strahlenbiologie, D-85764 Neuherberg, Ingolstädter Landstrasse 1, Germany
3 Ludwig Maximilian Universität, Institut für Strahlenbiologie, D-80336 München, Germany
4 Department of Clinical Oncology, The Churchill Hospital, Oxford OX3 7LJ, UK
5 ENEA, Department Health Effects (AMB-BIO), CRE-Casaccia, P.O. Box 2400 I-00100 Roma, Italy
6 IRSN, F-92265 Fontenay-aux-Roses, BP No 6, France
7 GSF-Forschungszentrum für Umwelt und Gesundheit, Institut für Pathologie, D-85764 Neuherberg, Germany
8 NRPB, National Radiological Protection Board, Chilton OX11 ORQ, UK

* Corresponding author: georg.gerber{at}pandora.be

The European Radiobiology Archives (ERA), supported by the European Commission and the European Late Effect Project Group (EULEP), together with the US National Radiobiology Archives (NRA) and the Japanese Radiobiology Archives (JRA) have collected all information still available on long-term animal experiments, including some selected human studies. The archives consist of a database in Microsoft Access, a website, databases of references and information on the use of the database. At present, the archives contain a description of the exposure conditions, animal strains, etc. from ~350,000 individuals; data on survival and pathology are available from ~200,000 individuals. Care has been taken to render pathological diagnoses compatible among different studies and to allow the lumping of pathological diagnoses into more general classes. ‘Forms’ in Access with an underlying computer code facilitate the use of the database. This paper describes the structure and content of the archives and illustrates an example for a possible analysis of such data.


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